Features of acute coronary syndrome associated with anxiety and depression disorders

Poponina T.M., Repin A.N., Poponina Y.S., Gunderina K.I.

Cardiovascular Diseases (CVDs) are a leading cause of death, with the highest mortality rates observed during exacerbations of Coronary heart disease (CHD). A high incidence of affective disorders has been demonstrated in patients after acute coronary syndrome (ACS), both in the inpatient and outpatient settings. The aim of this review is to present and analyze data from national and international studies on the features of ACS, associated with anxiety and depression disorders, published between 2016 and 2024.

Methods. The review was prepared using materials from peer-reviewed articles published on PubMed, eLIBRARY. RU, cyberleninka.ru, and the other resources from 2016 to 2024 were used.

Results. Along with well-established cardiovascular risk factors (RFs), such as arterial hypertension, smoking, and obesity, stress, anxiety, and depression are also recognized as risk factors. Due to hemodynamic disturbances in ACS, ischemic brain injuries may occur. These can lead to severe conditions, such as vascular delirium, as well as less severe disorders manifesting as cognitive impairment, sleep disorders, anxiety and/or depression.

Conclusion. To date, there are no clear, joint cardiology and psychiatry guidelines on diagnosis and management of psychiatric disorders in patients with ACS. Psychological and pharmacological interventions can have a positive effect and should be considered for ACS patients with depression, anxiety, and stress. Prior to discharge, all patients should be screened for mental disorders using validated questionnaires and, if necessary, a psychiatric consultation.

Keywords: Acute coronary syndrome, myocardial infarction, stress, anxiety, depression, risk factors, delirium, sudden cardiac death, antidepressants.

For citation: Poponina T.M., Repin A.N., Poponina Y.S., Gunderina K.I. Features of Acute Coronary syndrome associated with anxiety and depression disorders. 2025. 13(47):31-36. DOI: 10.24412/2311-1623-2025-47-39-45