Impact of omega-3 polyunsaturated fatty acids on cardiovascular systems

Kushnikova I. P., Nelidova N. V.

ABSTRACT

Long-term prospective cohort studies showed the association between high fish and omega-3 polyunsaturated fatty acids intake and lower risk of cardiovascular disease (CVD), especially coronary heart disease and myocardial infarction, as well as cardiovascular mortality in the general population. This review article analyses some of the key studies that have investigated the use of eicosapentaenoic and docosahexaenoic acids for primary and secondary prevention of CVD, discuss the mechanisms of its potential cardioprotective effects, and evaluates recently published randomized clinical trials in the context of existing scientific literature data.

Keywords: omega-3 polyunsaturated fatty acids, cardiovascular disease prevention, cardiovascular risk.

For citation:

Kushnikova  I. P., Nelidova  N. V. Impact of omega-3 polyunsaturated fatty acids on cardiovascular system. International Journal of Heart and Vascular Diseases. 2022. 10(36). 35-41. doi: 10.24412/2311-1623-2022-36-42-49